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Journal of Korean Diabetes ; : 310-314, 2015.
Article in Korean | WPRIM | ID: wpr-726846

ABSTRACT

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of oral antihyperglycemic drugs; inhibition of the cotransporter allows for increased renal glucose excretion that consequently leads to reduced plasma glucose level. We report a rare case of a 73-year-old woman with type 2 diabetes mellitus who developed severe ketoacidosis caused by an SGLT2 inhibitor. At admission, severe ketoacidosis with arterial PH 6.99 was observed, though her serum glucose level of 232 mg/dL was not excessively high. It is necessary to pay attention to patients with type 2 diabetes being treated with an SGLT2 inhibitor, as anorexia, diarrhea, dehydration, and weight loss can develop in conjunction with a high fat/protein diet.


Subject(s)
Aged , Female , Humans , Anorexia , Blood Glucose , Dehydration , Diabetes Mellitus , Diabetes Mellitus, Type 2 , Diabetic Ketoacidosis , Diarrhea , Diet , Glucose , Hydrogen-Ion Concentration , Ketosis , Weight Loss
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